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"DoubleTwist users will greatly benefit from the ability to easily access AlphaGene's significant sequence data, including over 50,000 potentially novel genes," said John Couch, chief executive officer of Pangea Systems.

Proprietary AlphaGene cDNA Sequence Data To Be Available Through DoubleTwist.com™

OAKLAND, CA, November 16, 1999 

DoubleTwist, Inc. (previously called Pangea Systems®) and AlphaGene, Inc. today announced an e-commerce partnership making 50,000 potentially novel genes available to every life scientist. The collaboration provides researchers with access to AlphaGene's proprietary cDNA sequence data through DoubleTwist.com, DoubleTwist's Internet portal for on-line genetic research. A DoubleTwist user researching a partial-length DNA sequence will automatically receive notification when a corresponding full-length cDNA exists in AlphaGene's database. AlphaGene will give the DoubleTwist user an opportunity to license or purchase the clone.

As a result of the AlphaGene partnership, DoubleTwist users will save time and money with the ability to immediately access and license full-length clones from AlphaGene's extensive libraries. DoubleTwist users will also gain the potential to discover novel genes from known EST's (expressed sequence tags) through access to AlphaGene's proprietary database.

"DoubleTwist users will greatly benefit from the ability to easily access AlphaGene's significant sequence data, including over 50,000 potentially novel genes," said John Couch, chief executive officer of DoubleTwist, Inc.. "Through relationships like this one, DoubleTwist is continuing to enable life scientists to simplify and accelerate on-line genetic research."

Ideal gene inventory display

"We are excited about this new channel for distributing our proprietary sequence data directly to researchers worldwide," said Donald McCarren, Ph.D., chief executive officer of AlphaGene. "We think DoubleTwist is an ideal mechanism for displaying AlphaGene's large gene inventory to the life science research community."

DoubleTwist is a leading-edge web portal integrating powerful and sophisticated research tools and data through an easy-to-use interface accessible to any life scientist interested in genetic research. The site uses automated search agents to seek out and interpret data based on the user's scientific questions, increasing the efficiency of conducting research and accelerating the gene discovery process. DoubleTwist is currently being validated at Stanford University and is scheduled for general commercial launch by January 2000.

DoubleTwist, Inc. is a leading provider of software and technologies for advanced bioinformatics -- the application of information technology to life science research and development. DoubleTwist's bioinformatics software and technologies simplify and accelerate the discovery process through powerful computational and data management processes. Incorporated in 1993, DoubleTwist is a privately held, Oakland, California-based company.

For more information, contact DoubleTwist at (510) 628-0100, or e-mail us at info-pr@doubletwist.com or visit http://www.doubletwist.com.

AlphaGene, Inc. is a functional genomics company developing novel technologies for gene discovery to accelerate drug development for major human diseases. Building upon its patented core technologies, AlphaGene has developed an integrated platform that includes gene arraying on biochips for identifying differentially expressed genes in disease or other cell states. AlphaGene also employs specialized assays and sophisticated bioinformatics to aid in the identification of critical disease-specific targets. The company is located in Woburn, Massachusetts.

For more information, contact AlphaGene, Inc. at (781) 933-4446 or email us at info@alphagene.com..

Copyright© 1999, DoubleTwist, Inc. All rights reserved. Pangea Systems and DoubleTwist.com are registered trademarks of DoubleTwist, Inc. The Pangea Systems, Doubletwist logo and the DoubleTwist.com logo are trademarks of DoubleTwist, Inc. All other trademarks, brands and names are property of their respective owners.

 

Contact:

Nicole Litchfield
DoubleTwist
510/628-0100

nicolel@pangeasystems.com

Joan Kureczka
J. Kureczka & Assoc.
415/821-2413

jkureczka@aol.com

Peter A. Schad, 
Chief Scientific Officer
AlphaGene, Inc.
781/933-4446 x236

pas@alphagene.com