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Bioinformatics Gene Expression Sequencing SLAGE

 

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Bioinformatics Capabilities

AlphaGene has developed substantial proprietary bioinformatics technology to support and extend the high-throughput capabilities of its integrated genomics platform.

AlphaGene's proprietary bioinformatics software supports four main functions:

A tracking system or LIMS collects, stores, and allows retrieval of information underlying every on-site process at AlphaGene. The bar-coded system minimizes handling errors and expedites high-throughput production. This results in a quality product and an "electronic lab book" that provides complete and rapid access to every process related data item;

A quality control system continuously monitors library and sequence production. Bioinformatics software automates feedback on DNA sequences, which facilitates the analysis of laboratory processes. This analysis allows high-throughput production without compromising quality;

AlphaGene's bioinformatics software builds a proprietary database containing partial sequence and finished full-length genes. Internal users can analyze and visualize data through a state-of-the-art World Wide Web interface on any computer platform. The database schema provides an efficient organization that makes retrieval and storage convenient and easily automatable;

Public algorithms perform automated and custom analysis for key genomics features from AlphaGene's database. Sequences are analyzed for homologies against public and proprietary databases. Novel genes with a high probability of being full-length and containing potentially important motifs can be annotated and stored.

 

AlphaGene, Inc.
260 W.
Cummings Park
Woburn, MA 01801
info@alphagene.com
781.933.4446 phone
781.933.5424 fax